Aim of research proposal

But it is important to keep it is an example of a second paragraph:To solve this problem we will develop an innovative mouse model system in which to study tax tumorigenesis using targeting vectors containing wild-type or mutant tax genes that are silenced by a preceding floxed stop vectors will be knocked in to the rosa26 locus of recipient mice by crossing these mice with lck-cre mice, the stop cassette will be specifically excised in developing thymocytes where the lck promoter is active, allowing conditional expression of wild-type or mutant tax proteins in t cells, the natural target of htlv-1 feasibility of our proposed mouse model is supported by the fact that lck-tax transgenic mice have been developed and produce a leukemia that closely resembles , targeting of tax expression in cells in which the lck promoter is active is expected to produce a similar disease in our our improved model system, insertion into the rosa26 locus will eliminate random integration sites and standardize gene copy number resulting in consistent levels of wild-type and mutant tax protein key:      long-term goal           proposal objective           rationale           hypothesis            2. The example given here is a strong example, but it is not specific aims page is unique to the ore, there is a lot of flexibility in how these elements can be arranged and emphasized.

Table of contentsdissertation proposals & writing dissertationsstep 1: dissertation proposalstitleintroductionaims and objectivesmethodologyliterature surveyscope and constraintsresourcestimetableoutline of sections/chaptersreferencesstep 2: what sections go into a dissertation? However, it should include the following components:Long-term goal: this is your overarching research e you are asking for support from a particular funding entity, it is important to ensure that your long-term goals align with the mission of your funding your wording general in this sentence—you are stating your long-term plans, and the reviewers understand that the specifics may be subject to esis and proposal objectives: your proposal should contain both of these components, depending on the long-term your central hypothesis clearly, specifically, and with simple want to demonstrate to the reviewers that you have a hypothesis-driven proposal that is be how your project addresses the critical need, and clearly state the proposed general, avoid vague hypotheses because it will be unclear to the reviewers what you expect to determine with the proposed ale: explain how you arrived at your central hypothesis (for example, using past studies and published literature).

Is some flexibility in this paragraph, depending upon how your proposal is structured and what your goals example, your research may be strictly hypothesis-driven and seek to test several elements of one general other cases, you may be seeking to develop a critical tool or technique in the on these variations, this paragraph will shape up differently. Components
research question
argument: why the research is important and worthwhile
philosophical stance, e.

Aims and objectives should not:Be too vague, ambitious or broad in repeat each other in different be a list of things related to your research dict your methods - i. Are no fixed number of aims or tutors are happy with one clear strong aim, whilst others like to see a main aim supported by at least two subsidiary will be required to produce sufficient objectives to be able to measure progress towards meeting the aim/ describe what you want to achieve.

Proposal headings
title page & table of contents
title
aims & objectives
introduction to the research topic
literature review
research design
ethical considerations
conclusions and recommendations
bibliography
. Including these is helpful to creating the impression that each aim is valuable, testable, and independent of the make it easier for the reviewers to clearly read and understand each aim, it is often helpful to use headings and/or bullets to delineate each specific is an example of the aims section:Aim 1 will establish an innovative mouse model for htlv-1 tax ing vectors containing silenced wild-type or mutant tax genes will be knocked in to the rosa26 locus of c57bl/6 mice will then be crossed with homozygous lck-cre mice, thereby excising the stop cassette and generating mice that express wild-type or mutant tax proteins specifically in t 2 will examine the effect of mutations that disable specific biological functions of tax on tax-mediated can bind to and regulate the activity of members of the srf, creb, nf-kb and pbm protein families, each of which has been implicated in established in aim 1 will allow us to compare for the first time the tumorigenic potential of wild-type and mutant tax proteins in an effort to identify pathways that are required for tax key:      aim title           experimental strategy           outcome or 3.

Objectives describe how you are going to achieve those eaim: to investigate the relationship between tectonic-plate movement and the gravitational effect of the alignment of the major ives:Data sets will be extracted from the known historical record of tectonic-plate sets will be extracted from astronomical tables detailing the various alignments of the major planets covering the same period as data from the geological data from both sets will be synthesised to establish if correlation points exist between major geological events and planetary alignments. Br />“good research proposals both give an overview of the project and a well informed discussion of the nuts and bolts of the proposed research” (burnett 2009)
connects with current literature
well though out, viable and timely
aware of strengths and limitations of your proposed approach
ethics
.

The literature and theoretical issues related to your your chosen subjects, respondents, units, goods or p a sampling frame and strategy or a rationale for their p a strategy and design for data collection and with ethical and practical problems in your research. Unported administrationbook administrationdownload as tation proposals & writing dissertations◄ previous: introduction next: methodology ►step 1: dissertation proposalsaims and objectivesthe primary focus of your research project is usually expressed in terms of aims and is the difference between an aim and an objective in an academic context?

Specific aims section is the most vital part of any nih grant this section, you must quickly gain the reviewers’ trust and confidence while simultaneously convincing them that your work is important to must also convey that you and your team are the best people to complete the work you’ve these reasons, the specific aims can be one of the most difficult sections to this article, we provide some tips on structure, content, and organization of your specific aims specific aims section is central to your grant ore, it should be the first section you may think of your specific aims page as an abbreviated version of the full having this page written and well-thought out, the remainder of grant application will be easier to introductory this paragraph, your goal should be to introduce your research subject to the reviewers and quickly capture their paragraph should describe the significant gap in knowledge that directly relates to the critical need the funding entity deals is critical to know your funding entity’s mission statement and ensure the critical need you are trying to fill fits well within its should include the following information:First sentence/hook: in this sentence, briefly describe what your proposal will be y, this sentence should convey a sense of importance or urgency to your n quickly what your research topic is and why it is critical that you conduct the research (i. And further and objectives it is often useful to consider your research questions in terms of aim(s) and objectives.

Sections of the paragraph have been color coded to highlight each critical er, your proposal may have some variability from these descriptions. Grant anatomy of a specific aims e date: aprit 09, 2015category: scientific grant writingauthor: michelle s.

Related slideshares at g a research farrell, digital learning specialist/academic hed on feb 2, is a brief introduction to writing a research proposal for a project or you sure you want message goes medicine physician at ukm medical ! The development of a new treatment, vaccine, disease model or diagnostic tool) include a broad impact statement about how your proposal will benefit the people or other subjects that you mentioned in the opening is an example of a final paragraph:The proposed studies will establish a new mouse model that will overcome current limitations and provide greater insight into the mechanism of htlv-1 tax tumorigenesis, knowledge that is currently lacking and that promises to yield novel insights into viral and cellular new and improved mouse model for tax tumorigenesis will provide a valuable resource for the wider scientific community to pursue a multitude of studies that have not previously been possible due to limitations of existing mouse models of key:      innovation           expected outcomes           impact/ 4.

Pagetitle pageacknowledgementsabstractcontents pagelist of figures or illustrationsmain body - introductionmain body - literature surveymain body - methodologymain body - resultsmain body - discussionmain body - recommendationsmain body - conclusionreference list/bibliographyappendiceswhat a dissertation should look liketitle pagenumbering sections and figurespage numbersformatpresentationbindingsubmitting your dissertationdissertation proposals & dissertation checklistavoiding plagiarismextra resourcesdownloadablesmore helpreturn to main pageskip creative commons licence© southampton solent university 2012. Consider the novelty, innovation, and significant elements of your proposal as you decide how to organize this page; however, a great specific aims page will possess all of these order presented here has an ideal logic for a majority of proposals, so try applying it to your proposal to see how it works for ific writing you like our articles, try our workshops!

These variations highlight the flexibility you have while creating a strong specific aims this section, you will describe briefly each of the aims you will use to test your y, the aims should be related, but not dependent, upon each you do this, the failure of one aim (or an unexpected result from one aim) does not negatively influence any other aim or prevent the completion of the other 2-4 sentences each, you should describe the experimental approach and how each aim will help answer your larger hypothesis. Is known: state what is currently known in the specific part should not be very long (3-5 sentences) but it should ground the reader in the subject of your e the reader with only the necessary details to understand why you are proposing the er to be concise and focused on only the key in knowledge: the gap in knowledge is the piece of information that is not y state the gap in knowledge that needs to be that your research will fill this gap using the funding that you are the example specific aims page we use here (see figure 1), the most critical piece of the gap in knowledge has been technique can be useful to emphasize the most important words or phrases in your specific aims you choose to use italics or underline to emphasize key points, remember to do so e of italics or underlining can be critical need: the critical need is the knowledge (hypothesis-driven), technique, new compound, or treatment that you propose to need is important to increase medically relevant knowledge or improve health critical need is the reason your proposal should be ize the significance of the problem you are trying to onally, it should be clear in this paragraph that your research proposes the next logical step to advance the is an example of an introductory paragraph:Viruses are thought to be involved in 15% to 20% of human cancers worldwide, thus providing critical tools to reveal common mechanisms involved in human the etiologic agent of adult t cell leukemia/lymphoma (atll), human t cell leukemia virus type i (htlv-1) is just such a -1 encodes a potent oncoprotein, tax, which regulates important cellular pathways including gene expression, proliferation, apoptosis, and the years, tax has proven to be a valuable model system in which to interrogate cellular processes, revealing pathways and mechanisms that play important roles in cellular gh the tax oncoprotein has been shown to transform cells in culture and to induce tumors in a variety of transgenic mouse models, the mechanism by which tax transforms cells is not well understood.

Here to return to our scientific editing article tation proposals & writing dissertations◄ previous: introduction next: methodology ►step 1: dissertation proposalsaims and objectivesthe primary focus of your research project is usually expressed in terms of aims and is the difference between an aim and an objective in an academic context? Whatever the case, your conclusion will still have to reflect on how well the research design, which was guided by your objectives has contributed to addressing your ty 20: aims & activity provides you with the opportunity to receive feedback on your proposed research aims and objectives.

Objectives
here the researcher talks about the purpose of the research
aims: general
objectives: specific
example aim: to evaluate the formal and informal processes of promotion within moon bank. Goal or a step on the way to meeting the aim; how you will achieve ives use specific statements which define measurable outcomes.

However, you may not always meet your aims in full, since your research may reveal that your questions were inappropriate, that there are intervening variables you could not account for or that the circumstances of the study have changed, etc. Avoid weaker verbs: collect, construct, classify, develop, devise, measure, produce, revise, select, synthesiseweak verbs: appreciate, consider, enquire, learn, know, understand, be aware of, appreciate, listen, many aims or objectives should there be?